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The DNA in a very human oocyte encompasses some 15 million nucleosomes — wrapping 2 times close to every one — forming an structured composition referred to as chromatin.
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Namekawa thinks that in human oocytes, modifications in these designs could disrupt the delicate choreography of genes staying turned on and off at the proper periods — leaving them unprepared for fertilization or development into balanced embryos. Alterations in chromatin structure being an oocyte ages might also impression the way that chromosomes segregate all through cell division.
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